Why was this study conducted? What does this study add? Is there anything else I should know? Turna J, Syan SK, Frey BN, Rush B, Costello MJ, Weiss M, MacKillop J. Cannabidiol as a novel candidate alcohol use disorder pharmacotherapy: a systematic review. Alcohol Clin Exp Res 2019; 43(4):550-563

Why was this study conducted? What does this study add? Is there anything else I should know? Hurd YL, Sprigss S, Alishayev J, Winkel G, Gurgov K, Kudrich C, Oprescu AN, Salsitz E. Cannabidiol for the reduction of cue-induced craving and anxiety in drug-abstinent individuals with heroin use disorder: A double-blind randomized placebo-controlled trial. Am J Psychiatry 2019;176:9110922

Why was this study conducted? What does this study add? Is there anything else I should know? Turna J, MacKillop J. Cannabis use among military veterans: A great deal to gain or lose? Clinical Psychology Review 2021; available online 11/1/2021

Why was this study conducted? What does this study add? Is there anything else I should know? Gajendran M, Sifuentes J, Bashashati M, McCallum R. Cannabinoid hyperemesis syndrome: definition, pathophysiology, clinical spectrum, insights into acute and long-term management. J Investig Med 2020;66:1309-1316

Why was this study conducted? What does this study add? Is there anything else I should know? Tibbo PG, McKee KA, Meyer JH, Crocker CE, Aitchison KJ, Lam RW, Crockford DN. Position Statement of the Canadian Psychiatric Association: Are there therapeutic benefits of cannabinoid products in adult mental illness? Can J Psychiatry 2020

Why was this study conducted? What does this study add? Is there anything else I should know? Starzer MSK, Nordentoft M, Hjorthoj C. Rates and predictors of conversion to schizophrenia or bipolaer disorder following substance-induced psychosis. American Journal of Psychiatry 2018;175:343-350.

Why was this study conducted? What does this study add? Is there anything else I should know? Purcell C., Davis A, Moolman N, Taylor SM. Reduction of benzodiazepine use in patients prescribed medical cannabis. Cannabis and Cannabinoid Research 2019;4(3): 214-218.

Why was this study conducted? What does this study add? Is there anything else I should know? Schoeler T, Theobald D, Pingualt J-B, Farrington DP, Jennings WG, Piquero AR, Coid JW, Bhattacharyya S. Continuity of cannabis use and violent offending over the life course. Psychological Medicine 2016;46:1663-1677.

Why was this study conducted? What does this study add? Is there anything else I should know? Roche DJO, Bujarski S, Green R, Hartwell EE, Leventhal AM, Ray LA. Alcohol, tobacco, and marijuana consumption is associated with increased odds of same-day substance co- and tri-use. Drug and Alcohol Dependence 2019;200:40-49.

Why was this study conducted? What does this study add? Is there anything else I should know? Dudovitz RN, Chung PJ, Reber S, Kennedy D, Tucker JS, Shoptaw S, Dosanjh KK, Wong MD. Assessment of exposure to high-performing schools and risk of adolescent substance use: a natural experiment. JAMA Pediatr 172(12):1135-1144 Accompanying editorial: Liljenquist KS, Coker TR. Addressing risky health behaviors among vulnerable youth through the school environment. Location, location, location. JAMA Pediatric 2018;172(12):1119-1120

Why was this study conducted? What does this study add? Is there anything else I should know? Gobbi G, Atkin T, Zytynski T, Wang S, Askari S, Boruff J, Ware M, Marmorstein N, Cipriani A, Dendukuri N, Mayo N. Association of cannabis use in adolescence and risk of depression, anxiety, and suicidality in young adulthood. A systematic review and met-analysis. JAMA Psychiatry Epub. February 13, 2019

Why was this study conducted? What does this study add? Is there anything else I should know? Turna J, Simpson W, Patterson B, Lucas P, Van Amerigen M. Cannabis use behaviors and prevalence of anxiety and depressive symptoms in a cohort of Canadian medicinal cannabis users. J Psychiatr Res 2019; 111L134-149

Why was this study conducted? What does this study add? Is there anything else I should know? Zhang H, Xie M, Archibald SD, Jackson BS, Gupta MK. Association of marijuana use with psychosocial and quality of life outcomes among patients with head and neck cancer. JAMA Otolaryngol Head Neck Surg 2018;144(11):1017-1022

Why was this study conducted? What does this study add? Is there anything else I should know? Spindle TR, Cone EJ, Schlienz NJ, Mitchell JM, Bigelow GE, Flegel R, Hayes E, Vandrey R. Acute effects of smoked and vaporized cannabis in healthy adults who infrequently use cannabis, a crossover trial. JAMA Network Open 2018;1(7):e184841 Invited commentary: Solowij N. Peering through the haze of smoked vs vaporized cannabis – to vape or not to vape? JAMA Network Open 2018;1(7):e184838

Why were these studies conducted? What do these studies add? Is there anything else I should know? Bradford AC, Bradford WD, Abraham A, Adams BG. Association between US state medical cannabis laws and opioid prescribing in the medicare Part D Population. JAMA Intern Med 2018; Published online April 2, 2018 doi:10.1001/jamainternmed.2018.0266 Wen H, Hockenberry JM. Association of medical and adult-use marijuana laws with opioid prescribing for Medicaid enrollees. JAMA Intern Med 2018; Publish online April 2, 2018. Doi: 10.1001/jamainternmed.2018.1007.

Why was this study conducted? What does this study add? Is there anything else I should know? Staples JA, Redelmeier DA. The April 20 cannabis celebration and fatal traffic crashes in the United States [Letter]. JAMA Internal Med 2018; 178(4):459-571

Why was this study conducted? What does this study add? Is there anything else I should know? Shalev A, Liberzon I, Marmar C. Post-traumatic stress disorder. N Engl J Med 2017;376(25):2459-2469

Why was this study conducted? What does this study add? Is there anything else I should know? Volkow ND, Baler RD, Compton WM, Weiss SR. Adverse health effects of marijuana use. N Engl J Med 2014;370(23):2219-27

Why was this study conducted? What does this study add? Is there anything else I should know? Curran HV, Freeman TP, Mokrysz C, Lewis DA, Morgan CJ, Parsons LH. Keep off the grass? Cannabis, cognition and addiction. Nat Rev Neurosci 2016; 17(5):293- 306

Why was this study conducted? What does this study add? Is there anything else I should know? Turna J, Patterson B, Van Ameringen M. Is cannabis treatment for anxiety, mood, and related disorders ready for prime time? Depress Anxiety 2017;doi: 1002/da.22664 (Epub ahead of print)

Why was this study conducted? What does this study add? Is there anything else I should know? Hryhorowicz S, Walcsak M, Zakerska-Banaszak O, Slomski R, Skrzypczak-Zielinska M. Pharmacogenetics of cannabinoids. Eur J Drug Metab Pharmacokinet 2018;43:1-2

Why was this study conducted? What does this study add? Is there anything else I should know? Anderson DM, Hansen B, Rees DI, Sabia JJ. Association of Marijuana Laws with Teen Marijuana Use: New Estimates from the Youth Risk Behavior Surveys. JAMA Pediatrics 2019;173(9):879-881.

Why were these studies conducted? What do these studies add? Is there anything else I should know? Bradford AC, Bradford WD, Abraham A, Adams BG. Association between US state medical cannabis laws and opioid prescribing in the medicare Part D Population. JAMA Intern Med 2018; Published online April 2, 2018 doi:10.1001/jamainternmed.2018.0266 Wen H, Hockenberry JM. Association of medical and adult-use marijuana laws with opioid prescribing for Medicaid enrollees. JAMA Intern Med 2018; Publish online April 2, 2018. Doi: 10.1001/jamainternmed.2018.1007.

Why was this study conducted? What does this study add? Is there anything else I should know? Staples JA, Redelmeier DA. The April 20 cannabis celebration and fatal traffic crashes in the United States [Letter]. JAMA Internal Med 2018; 178(4):459-571

Why was this study conducted? What does this study add? Is there anything else I should know? Rubin R. Medical marijuana is legal in most states but physicians have little evidence to guide them. JAMA 2017;317(16):1611-1613

Why was this study conducted? What does this study add? Is there anything else I should know?

Why was this study conducted? What does this study add? Is there anything else I should know? Bartlett K, Kaarid K, Gervais N, Vu N, Sharma S, Patel T, Shea AK. Pregnant Canadians’ perceptions about the transmission of cannabis in pregnancy and while breastfeeding and the impact of information from health care providers on discontinuation of use. J Obstet Gynaecol Can 2020;42(11):1346-1350 Vanstone M, Taneja S, Popoola A, Panday J, Greyson D, Lennox R, McDonald SD. Reasons for cannabis use during pregnancy and lactation: a qualitative study. CMAJ 2021;193: E1906-14

Why was this study conducted? What does this study add? Is there anything else I should know? Walker OS, Holloway AC, Raha S. The role of the endocannabinoid system in female reproductive tissues. J Ovarian Res 2019;12:3 Martinez-Pena AA, Perono GA, Gritis SA, Sharma R, Selvakumar S, Walker OS, Gurm H, Holloway AC. The impact of early life exposure to cannabis: the role of the endocannabinoid system. Int J Molecular Sci 2021;22:8576

Why was this study conducted? What does this study add? Is there anything else I should know? Kozak T, Ion A, Greene S. Reimagining research with pregnant women and parents who consume cannabis in the era of legalization: the value of integrating intersectional feminist and participatory action approaches. Cannabis and Cannabinoid Res Published online: 9 Dec 2020; https://doi.org/10.1089/can.2020.0086

Why was this study conducted? What does this study add? Is there anything else I should know? Turna J, Syan SK, Frey BN, Rush B, Costello MJ, Weiss M, MacKillop J. Cannabidiol as a novel candidate alcohol use disorder pharmacotherapy: a systematic review. Alcohol Clin Exp Res 2019; 43(4):550-563

Why was this study conducted? What does this study add? Is there anything else I should know? Turna J, MacKillop J. Cannabis use among military veterans: A great deal to gain or lose? Clinical Psychology Review 2021; available online 11/1/2021

Why was this study conducted? What does this study add? Is there anything else I should know? Ng JY, Garber A, Luong M, Cooley K, Busse JW. No improvement in disclosure of natural health product use to primary care medical doctors in the last 15 years: A survey of naturopathic patients. Complementary Therapies in Clinical Practice 2020;19:101-106

Why was this study conducted? What does this study add? Is there anything else I should know? Dai H, Richter KP. A National Survey of Marijuana Use Among US Adults with Medical Conditions, 2016-2017. JAMA Network Open 2019;p2(9):e1911936

Why was this study conducted? What does this study add? Is there anything else I should know? Humphreys K, Saitz R. Should physicians recommend replacing opioids with cannabis? (Viewpoint) JAMA 2019;321(7):639-640

Why was this study conducted? What does this study add? Is there anything else I should know? Weizman L, Dayan L, Brill S, Nahman-Averbuch H, Hendler T, Jacob G, Sharon H. Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity. Neurology 2019;91:e1285-e1294

Why was this study conducted? What does this study add? Is there anything else I should know? Spencer N, Shaw E, Slaven M. Medical cannabis use in an outpatient palliative care clinic: A retrospective chart review. J Pain Manage 2016;9(4):507-513

Why was this study conducted? What does this study add? Is there anything else I should know? Busse J (ed). The 2017 Canadian guideline for opioids for chronic non-cancer pain. National Pain Centre, McMaster University. 2017.

Why was this study conducted? What does this study add? Is there anything else I should know? Hill KP. Medical marijuana for treatment of chronic pain and other medical and psychiatric problems, a clinical review. JAMA 2015;313(24):2474-83

Why was this study conducted? What does this study add? Is there anything else I should know? Brubacher JR, Chan H, Erdelyi S, Staples JA, Asbridge M, Mann RE. Cannabis legalization and detection of tetrahydrocannabinol in injured drivers. NEJM 2002;386:148-56

Why was this study conducted? What does this study add? Is there anything else I should know? Bartlett K, Kaarid K, Gervais N, Vu N, Sharma S, Patel T, Shea AK. Pregnant Canadians’ perceptions about the transmission of cannabis in pregnancy and while breastfeeding and the impact of information from health care providers on discontinuation of use. J Obstet Gynaecol Can 2020;42(11):1346-1350 Vanstone M, Taneja S, Popoola A, Panday J, Greyson D, Lennox R, McDonald SD. Reasons for cannabis use during pregnancy and lactation: a qualitative study. CMAJ 2021;193: E1906-14

Why was this study conducted? What does this study add? Is there anything else I should know? Walker OS, Holloway AC, Raha S. The role of the endocannabinoid system in female reproductive tissues. J Ovarian Res 2019;12:3 Martinez-Pena AA, Perono GA, Gritis SA, Sharma R, Selvakumar S, Walker OS, Gurm H, Holloway AC. The impact of early life exposure to cannabis: the role of the endocannabinoid system. Int J Molecular Sci 2021;22:8576

Why was this study conducted? What does this study add? Is there anything else I should know? Kozak T, Ion A, Greene S. Reimagining research with pregnant women and parents who consume cannabis in the era of legalization: the value of integrating intersectional feminist and participatory action approaches. Cannabis and Cannabinoid Res Published online: 9 Dec 2020; https://doi.org/10.1089/can.2020.0086

Why was this study conducted? What does this study add? Is there anything else I should know? Wallingford S, Konefai S, Young MM. 2019 Cannabis Use, Harms and Perceived Risks among Canadian Students. Technical Report. 2019; Ottawa Ont: Canadian Centre on Substance Use and Addiction.

Why was this study conducted? What does this study add? Is there anything else I should know? Els C, Jackson TD, Tsuyuki FT, Aidoo H, Wyatt G, Sowah D, Chao D, Haoffman H, Kunyk D, Milen M, Stewart-Patterson C, Dick BD, Farnan P, Straube S. Impact of cannabis use on road traffic collisions and safety at work: systematic review and meta-analysis. Canadian Journal of Addition 2019;10(1):8-15.

Why was this study conducted? What does this study add? Is there anything else I should know? Fish EW, Murdaugh LB, Zhang C, Boschen KE, Boa-Amponsem O, Mendoza-Romero HN, Tarpley M, Chdid L, Mukhopadhyay S, Cole GJ, Williams KP, Parnell SE. Cannabinoids exacerbate alcohol teratogenesis by a CD1-Hudgehog interaction. Scientific Report 2019;9:16507

Why was this study conducted? What does this study add? Is there anything else I should know? Ng JY, Garber A, Luong M, Cooley K, Busse JW. No improvement in disclosure of natural health product use to primary care medical doctors in the last 15 years: A survey of naturopathic patients. Complementary Therapies in Clinical Practice 2020;19:101-106

Why was this study conducted? What does this study add? Is there anything else I should know? Dai H, Richter KP. A National Survey of Marijuana Use Among US Adults with Medical Conditions, 2016-2017. JAMA Network Open 2019;p2(9):e1911936

Why was this study conducted? What does this study add? Is there anything else I should know? Aguiar JA, Huff RD, Tse W, Stampfli MR, McConkey BJ, Doxey AC, Hirota JA. Transcriptomic and barrier responses of human airway epithelial cells exposed to cannabis smoke. Physiological Report 2019;7(20):e14249

Why were these studies conducted? What do these studies add? Is there anything else I should know? Bradford AC, Bradford WD, Abraham A, Adams BG. Association between US state medical cannabis laws and opioid prescribing in the medicare Part D Population. JAMA Intern Med 2018; Published online April 2, 2018 doi:10.1001/jamainternmed.2018.0266 Wen H, Hockenberry JM. Association of medical and adult-use marijuana laws with opioid prescribing for Medicaid enrollees. JAMA Intern Med 2018; Publish online April 2, 2018. Doi: 10.1001/jamainternmed.2018.1007.

Why was this study conducted? What does this study add? Is there anything else I should know? Staples JA, Redelmeier DA. The April 20 cannabis celebration and fatal traffic crashes in the United States [Letter]. JAMA Internal Med 2018; 178(4):459-571

Why was this study conducted? What does this study add? Is there anything else I should know? Friedman D, Devinsky O. Cannabinoids in the treatment of epilepsy. N Engl J Med 2016;374(1):94-5

Why was this study conducted? What does this study add? Is there anything else I should know? Vandrey R, Raber JC, Rabert ME et al. Cannabinoid doses and label accuracy in edible medical cannabis products. JAMA 2015;313(24):2491-2494.